Instant hand sanitizer delivers advanced germ-kill while being very kind to the skin. PURELL Advanced Instant Hand Sanitizer kills more than 99.99 percent of most common germs. This alcohol-based hand sanitizer works in as little as 15 seconds with no water or towels needed. The 1200 ml. TFX refill provides unprecedented germ-kill while soothing hands and maintaining skin health. PURELL Advanced is enhanced with four different skin-conditioning agents that help maintain skin health and skin moisture and improves overall skin feel. Refill snaps securely into place with an audible click and includes a fresh dispensing valve. Sanitary-sealed, collapsible-bottle refill keeps germs out.